Heart of Inflammation

Animations and 3D visuals produced to reinforce the pathophysiology concepts on, an HCP resource that communicates the central role of the inflammatory cytokine IL-1 in recurrent pericarditis. Interleukin-1 (IL-1) is a family of cytokines that includes IL-1α and IL-1β -- cell signaling proteins that activate local and systemic inflammation. Interaction between IL-1α and IL-1β triggers the autoinflammatory cycle of recurrent pericarditis and drives ongoing tissue injury in the pericardium.

3D Production: Newt Studios
Agency: MERGE
Client: Kiniksa

Looping animation of IL-1 cytokines swarming and triggering inflammation in the heart's pericardium.

Looping animation of IL-1α and IL-1β building to form IL-1 -- the master cytokine of inflammation.

Heart and Pericardium -- 3D Modeling Process

Heart Animation -- Particles setup and animatics

IL-1 Master Cytokine -- Style development

IL-1 Animation -- Particles Setup

Heart Visual -- Organic Style development

Heart Visual -- Star-field Style development

Heart Visual -- Glass Style development

Light-bulb Visual -- Style development

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